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Ausgabe
März 2008
Graspollenallergie: Welche Pollenkonzentration löst Symptome
aus?
Erste Symptome stellen sich
bei Graspollenallergie bereits bei einer Konzentration von 20
Pollen in 1 einem Kubikmeter Luft ein (bei rund 25% der Allergiker). Steigt die
Konzentration auf 50 Pollen in einem Kubikmeter Luft so geben alle
Allergiker die quälenden Symptome zu Protokoll. Werden Allergiker mehrere
Stunden lang Pollenkonzentrationen von mehr als 120 Pollen in einem
Kubikmeter Luft ausgesetzt, so stellt sich bei einigen Patienten sogar
Atemnot ein.
Das Auftreten von
Allergie-Symptomen hängt aber nicht nur von der Menge der Allergene
(Pollen) ab, sondern auch von der Art der Allergene.
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Eine vollständige englischsprachige Kurzversion
dieser Studie
(sog. MEDLINE Abstract) finden Sie
hier
Abstract:
The purpose of this study was to analyze the relation between
clinical picture of allergic disease and the level of pollen count
the patients are exposed to.
MATERIAL AND METHOD: We analyzed the severity of allergic
rhinitis, conjunctivitis and bronchial asthma in a group of 640
subjects from Warsaw area with hypersensitivity to hazel, alder,
grass, mugwort, plantain, nettle, Alternaria and Cladosporium
allergens. Aerobiological measurements, patients' symptoms score
cards and the results of physical examination were analyzed.
RESULTS: First symptoms in patients allergic to grass were
visible during exposure to the concentration of 20 pollen grains in
1 m3 of air (25% subjects sensitised to grass pollen). Symptoms were
noted in all the subjects sensitized to grass pollen at a
concentration of approximately 50 grains/m3 of air. During exposure
to the concentration of 65 pollen grains per m3 the symptoms were
strengthened. Several hours' exposure to grass pollen concentration
exceeding 120 grains/m3 cause dyspnoea in some patients. Similar
intensive symptoms occurred after exposure to alder, birch and
mugwort pollen. Patients with positive skin prick tests to plantain
and nettle pollen allergens experienced symptoms of low intensity or
even none symptoms during pollination period.
Subjects with
hypersensitivity to Alternaria allergens experienced symptoms during
exposure to the concentration of approximately 80 spores in 1 m3 of
air, while patients sensitised to Cladosporium allergens, during
exposure to the concentration of over 2800 spores in
1 m3 of air.
The dominant symptom occurring in patients sensitized to fungal
allergens was loss of nasal patency, and dyspnoea as well as
recurring cough at higher concentrations.
CONCLUSIONS: Clinical symptoms of allergic disease were
connected to the concentration and the kind of aeroallergen the
subjects were exposed to.
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